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Study Finds COVID mRNA Vaccine Components Persist Over 3.5 Years

For years, the public was assured that COVID-19 mRNA vaccine materials would degrade within days or weeks—rapidly broken down, biologically transient, and incapable of long-term persistence. Those assurances shaped regulatory approvals, public messaging, and a global vaccination campaign involving billions of people. New findings now directly challenge that foundational narrative. A coordinated, multi-year investigation involving…

For years, the public was assured that COVID-19 mRNA vaccine materials would degrade within days or weeks—rapidly broken down, biologically transient, and incapable of long-term persistence. Those assurances shaped regulatory approvals, public messaging, and a global vaccination campaign involving billions of people.

New findings now directly challenge that foundational narrative.

A coordinated, multi-year investigation involving the McCullough Foundation, INMODIA Laboratory (Germany), Dresden-Friedrichstadt Municipal Hospital, Neo7Bioscience, and cooperating independent laboratories reports the longest documented persistence to date of vaccine-derived mRNA, plasmid DNA fragments, and spike protein in a human subject—more than 3.5 years after vaccination.

What the Study Examined
The report, titled “Unprecedented Persistence of Vaccine mRNA, Plasmid DNA, Spike Protein, and Genomic Dysregulation Over 3.5 Years Post–COVID-19 mRNA Vaccination,” documents an exceptionally comprehensive longitudinal case.

The investigation includes over 40 emergency room visits, more than 200 specialist consultations across 18 medical disciplines, over 100 laboratory tests, more than 100 imaging and functional studies, and serial blood and tissue sampling spanning more than three and a half years.

The subject was a 55-year-old man who received three doses of the Pfizer–BioNTech mRNA vaccine and subsequently developed progressive multi-organ dysfunction consistent with what clinicians describe as post-COVID-19 vaccine syndrome (PCVS).

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Infection Was Effectively Ruled Out
A critical component of the investigation was excluding prior SARS-CoV-2 infection as a confounding factor.

Across five separate time points, confirmed by three independent laboratories, the patient remained negative for nucleocapsid antibodies, a marker of natural infection. Nucleocapsid protein was also absent from tissue samples, even as spike protein was repeatedly detected.

Despite this, spike-specific antibody levels remained markedly elevated 1,433 days after the last vaccination, indicating ongoing antigenic stimulation rather than residual immunity from infection.

What Researchers Found
Using multiple analytical methods—including ELISA, RT-PCR, standard PCR with Sanger sequencing, automated immunohistochemistry, whole-genome sequencing, transcriptomics, and quantitative mass spectrometry—researchers identified:

  • Spike protein in circulating immune cells, plasma, exosomes, endothelial tissue, macrophages, and nerve fibers
  • Vaccine-derived spike mRNA in circulating exosomes more than 1,200 days post-vaccination
  • Plasmid DNA elements (including spike gene regions and SV40 enhancer sequences) in skin tissue 1,364 days post-vaccination

All findings were independently confirmed across multiple laboratories, biological compartments, and time points.

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Genomic and Molecular Dysregulation
Beyond persistence of vaccine-derived material, multi-omics analysis revealed widespread molecular disruption.

Whole-genome sequencing identified structural variants and genomic instability affecting key regulatory genes including EGFR, MYC, ERBB2, and TP53-related pathways. Transcriptomic profiling showed patterns consistent with oxidative stress, vascular activation, and nuclear fragility.

Urine proteomics confirmed systemic inflammation, complement overactivation, and persistent immune signaling long after vaccination.

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Why This Matters
This case documents the longest reported in vivo persistence of vaccine-derived genetic material and spike protein to date. The findings directly contradict the repeated claim that mRNA vaccine components are rapidly degraded and biologically short-lived.

The authors emphasize that this is a case report, not a population-level prevalence study. Still, the consistency of findings across time, tissue, and methodology raises questions that demand further investigation—not dismissal.

When institutions insist the science is “settled,” independent analysis becomes critical. Dr. Bryan Ardis has repeatedly warned about biological assumptions that collapse under real-world data. His work has helped many recognize patterns long before they were acknowledged publicly.

Conclusion
The global COVID-19 vaccination campaign was built on assurances about the transient nature of mRNA vaccine components. This investigation presents molecular evidence that, at least in some cases, those assurances were incomplete.

Persistent vaccine-derived mRNA, plasmid DNA fragments, and spike protein—confirmed years after vaccination—represent findings that cannot be ignored.

These implications are not political. They are biological.

And they demand transparent, rigorous follow-up.

If you want to stay grounded when narratives shift and institutions scramble, anchoring matters. If you read one book to keep perspective as medical dogma unravels, make it this.


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After much research, the following supplements can prevent Covid and other viruses. My family and I mainly follow the protocol of Dr Bryan Ardis. This is only my opinion based on my own family’s success. Please make sure you do your own research and speak with your medical professional before making any changes to your health routine.

EDTA
Glutathion
NAC
Zinc
Vitamin C (Ascorbic Acid)
Vitamin D3
Quercetin
Cats Claw
Nicotine
Bromelain
Curcumin

Dr. McCullough recommends taking this treatment triad for at least three months for anyone suffering from or worried about post-COVID or post-vaccine syndromes.

NattokinaseBromelain, and Curcumin are available over the counter at just about any health food store or pharmacy.

Selenium 
Dandelion Root 
Black Sativa Extract (may facilitate cellular repair)
Green Tea Extract (provides added defenses at the cellular level through scavenging for free radicals)
Irish Sea Moss (could help rebuild damaged tissue and muscle)

In an acute emergency, if you get Covid, Dr Ardis suggests taking low doses of Nicotine in the form of LozengesGum, or Patches for a few days until symptoms subside.