Vaccines are pitched as being an illness preventer. However, a study from almost one year ago might determine an exactly opposite fate by those children who are given a vaccine.
The study, printed in the New England Journal of Medicine, found that when children received three doses of the malaria vaccine, it created a “negative efficacy.” Kids who received three doses of the vaccine actually contracted malaria MORE OFTEN than kids who didn’t.
Over 7 years of follow-up, we identified 1002 episodes of clinical malaria among 223 children randomly assigned to the RTS,S/AS01 group and 992 episodes among 224 children randomly assigned to the control group. The vaccine efficacy, as assessed by negative binomial regression, was 4.4% (95% confidence interval [CI], ?17.0 to 21.9; P=0.66) in the intention-to-treat analysis and 7.0% (95% CI, ?14.5 to 24.6; P=0.52) in the per-protocol analysis. Vaccine efficacy waned over time (P=0.006 for the interaction between vaccination and time), including negative efficacy during the fifth year among children with higher-than-average exposure to malaria parasites (intention-to-treat analysis: ?43.5%; 95% CI, ?100.3 to ?2.8 [P=0.03]; per-protocol analysis: ?56.8%; 95% CI, ?118.7 to ?12.3 [P=0.008]). (Click to Article)